Dr. Sindhu Mathai received her Ph. D. from Cochin University of Science and Technology in February 2005, and the research work was carried out at CSIR-NIIST, Trivandrum, under the guidance of Dr. G. Vijay Nair. During her doctoral studies, she worked on ‘Novel 1,3-dipolar cycloaddition reactions of acyclic carbonyl ylides and related chemistry’. Subsequently, she joined as a post-doctoral fellow (2005-2006) under the direction of Prof. Alan R. Katritzky, University of Florida, to investigate the synthesis of triazole polymers as potential rocket propellant binders. Afterward, she received the Alexander von Humboldt Fellowship to pursue her research (2006-2008) at Regensburg University, Germany, under the guidance of Prof. Dr. Oliver Reiser. While working as an Alexander von Humboldt Fellow, she was engaged in the multi-step total synthesis of biologically active natural products like Chinensiolides; members of the Guaianolide family. She returned to India in May 2008 and joined Lupin R

Development of novel methodologies in organic synthesis, Development of polymers for organic solar cells, Heterogeneous catalysis, Synthesis of bioactive molecules with special emphasis on antiviral drugs

Highly atom efficient synthesis of 2,2,4,5- tetrasubstituted 3(2H)-furanones having both hydroxyl and amino substituents, Synthetic Communications, Taylor & Francis Vol. 52, 2022

Preparation and mechanical properties of crosslinkd 1,2,3-triazole-polymers as potential propellant binders, Journal of Applied Polymer Science, Wiley Vol. 117, 2010

Preparation and characterization of 1,2,3-triazole-cured polymers from endcapped azides and alkynes, Journal of Polymer Science Part A Polymer Chemistry, Wiley Vol. 46, 2008

Stereoselective synthesis of highly substituted tetrahydrofuran derivatives via Huisgen 1,3-dipolar cycloaddition of acyclic carbonyl ylides to activated styrenes, Research on Chemical Intermediates, Springer Vol. 32, 2006

A stereoselective synthesis of spiro-dioxolanes via the multicomponent reaction of dicarbomethoxycarbene, aldehydes and 1,2- or 1,4-diones, Tetrahedron , Elsevier Vol. 61, 2005

The Huisgen reaction of azomethine ylide to isatins: A facile synthesis of spiro-oxindoles, Synthesis, Thieme Vol. 16, 2004

The Rh(II)-catalyzed reaction of diethyl diazomalonate with thietanes: a facile synthesis of tetrahydrothiophene derivatives via sulfonium ylides, Tetrahedron Letters, Elsevier Vol. 45, 2004

The three-component reaction of dicarbomethoxycarbene, aldehydes, and ?-nitrostyrenes: a stereoselective synthesis of substituted tetrahydrofurans, Journal of Organic Chemistry, American Chemical Society Vol. 69, 2004

A facile three-component reaction of dicarbomethoxycarbene, aldehydes and o-quinones: synthesis of novel spiro- dioxolanes, Tetrahedron Letters, Elsevier Vol. 44, 2003

Bromination of cyclopropanes using potassium bromide and cerium(IV) ammonium nitrate (CAN): synthesis of 1,3-dibromides, Research on Chemical Intermediates, Springer Vol. 24, 2003

. Investigations towards the Synthetic Applications of Gallium (III)triflate as a Superior Lewis acid Catalyst in Organic Transformations, National Seminar on New Frontiers in Theoretical Chemistry (NFTC), 2018

Investigations towards the total synthesis of Chinensiolide B: A naturally Occurring Guaianolide, Current Trends in Organic and Medicinal Chemistry, 2016

Dr. SINDHU MATHAI, Book of Abstracts, Department of Applied Chemistry, CUSAT, 2020

Dr. SINDHU MATHAI, Anitha Koshy, Proceedings of the National Seminar on Current Trends in Organic and Medicinal Chemistry, Catholicate College, Pathanamthitta, 2016 , ISBN : 978-93-5258-618-9

Resource Person, National Science Day 2020, sponsored by KSCSTE from Catholicate College, Pathanamthitta, in the year 2020

RESEARCH PROJECTS

"Investigations towards the Synthetic Applications of Ga(III)triflate as a superior Lewis Acid Catalyst in Organic Transformations" (UGC- 2014 --0001 , Total outlay Rs.101000)

"Investigations on the dipolar cycloaddition reactions of azomethine imines with 1,2-diones, 1,4-diones and bisarynes: Synthesis of novel structurally important heterocycles" (UGC-BSR Start-up Research Grant- 2021 --0001 , Total outlay Rs.10000)

"Novel heterogeneous palladium catalysts based on sterically hindered N-heterocyclic carbenes for coupling reactions: A green synthetic methodology" (University- 2021 --0001 , Total outlay Rs.275000)

PATENT

Novel protein tyrosine phosphatase-1B inhibitors - accepted,2009