Dr T.P. Sajeevan has more than 20 years of research experience in marine biotechnology and marine bioprospecting for bioactive compounds and focuses on the isolation and characterization of natural products from marine-derived microorganisms, especially actinomycetes, that have promising biological activity. Dr Sajeevan has participated in sea cruises, including arctic expedition (36 days) and collected marine samples from the different marine environments. Recently his group discovered and described a novel bacterial genus, Roseitranquillus sediminis (Umar et al 2021), and a novel species of rare actinomycetes with cytotoxic activities Pseudonocardia cytotoxica (Dhaneesha et al 2021) from Arctic fjord. The research group has active programs in marine microbiology, bioprospecting for novel small molecules with diverse bioactivities. Our research program is highly collaborative, working with many international research groups in the USA (Scripps Institutions of Oceanography, University

marine biological resources , marine chemical ecology, Marine Drug Discovery, marine microbial diversity, marine natural products

Google Scholar

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https://scholar.google.com/citations?hl=en&authuser=1&user=KWljDGgAAAAJ

Applications of Actinobacteria in aquaculture: prospects and challenges, 3 Biotech, 2023

Hidden in the photograph: The myth of complete metabolic coverage possible in metabolomics investigations, Analytical Science Advances, 2023

Genomic insights into symbiosis and host adaptation of an ascidian associated bacterium Bacillus aryabhattai MCCB 387, Symbiosis, 2022

Molecular characterization and expression analysis of two type 1 Interferons from Asian Seabass (Lates calcarifer) during Nervous Necrosis Virus infection, Aquaculture Research, 2022

Molecular characterization and expression analysis of two RING-between-RING (RBR) ubiquitin ligase orthologues from the Asian Seabass (Lates calcarifer) , Aquaculture International, 2022

Antiviral radical SAM enzyme viperin homologue from Asian seabass (Latescalcarifer): molecular characterisation and expression analysis, Developmental and Comparative Immunology , 2022

Targeted isolation of two new anti-inflammatory and UV-A protective dipyrroloquinones from the sponge-associated fungus Aspergillus tamarii MCCF102, Planta Medica, 2022

Identification of two ISG15 homologues involved in host immune response against RGNNV in Asian seabass (Lates calcarifer), Fish and Shellfish immunology Reports , 2022

Roseitranquillus sediminis gen. nov., sp. nov. a novel genus and species of the family Rhodobacteraceae, isolated from sediment of an Arctic fjord , Antonie van Leeuwenhoek, Springer 2021

Folate Functionalized Chitosan Nanoparticles as Targeted Delivery Systems for improved anticancer efficiency of Cytarabine in MCF -7 human breast cancer cell lines, International Journal of Biological Macromolecules, 2021

Prof. Dr. SAJEEVAN T.P, Rosamma Philip, E.V. Radhakrishnan, Immunostimulants in Aquaculture, Aquaculture Authority and NCAAH, 2005

Raman Postdoctoral Fellows to do advanced research in USA (UTSW, Dallas, USA) from UGC, Govt. of India, in the year 2016

Expedition member in the ‘Indian Arctic Expedition 2014’ from NCPOR, Ministry of Earth Sciences, Govt. of India, in the year 2016

Visiting researcher at Scripps Institution of Oceanography, California, USA from UGC, in the year 2016

Visiting researcher at Scripps Institution of Oceanography, California, USA from UGC, in the year 2019

RESEARCH PROJECTS

"Bioactive peptides and Depsipeptides with potential anticancer activity from marine sponges and tunicates of Indian Ocean (PI)." (Kerala State Council for Science, Technology and Environment- 2015 -2018 , Total outlay Rs.2465600)

"Molecular screening, cell culture based isolation and characterization of finfish and shellfish viruses and establishment of National Repository (PI)." (Department of Biotechnology, Govt. of India- 2017 -2020 , Total outlay Rs.11866000)

"Bioprospecting for Neuroprotective compounds from an endosymbiotic fungi Aspergillus sp. MCCF102 isolated form a marine sponge as potential drug candidates against neurodegenerative disorders (PI)." (Department of Biotechnology, Govt. of India- 2019 -2022 , Total outlay Rs.5388600)

"Microbiome of Glaciomarine system of Svalbard; diversity and its variability (Co-PI)" (Minstry of Earth Sciences- 2019 --0001 , Total outlay Rs.4084300)

"Bioprospecting of Marine microbial diversity for various products under the Marine Bioresource and Biotechnology Network Programme (PI)." (DBT- 2021 -2024 , Total outlay Rs.8304160)

"Bioprospecting for antitumor molecules from marine actinomycetes (PI)." (UGC, Govt.of India- 2012 -2014 , Total outlay Rs.383000)

"Isolation and chemical characterisation of anticancer metabolites from marine actinomycetes and elucidation of mechanisms anticancer activity through Functional Signature Ontology (FUSION) mapping( UGC Raman Postdoctoral Fellow to do research at U" (UGC, Govt.of India- 2016 -2017 , Total outlay Rs.2500000)

"Indo-US initiatives on innovative reforms in marine biotechnology education and research and development of sustainable aquaculture production systems for inclusive economic growth and sustainable development (Co-PI)" (UGC, Govt.of India- 2015 -2018 , Total outlay Rs.12529000)

"Marine synthetic biology: building national capacity and human resources (Co-PI) " (DBT- 2017 -2020 , Total outlay Rs.5149000)

"Nutritional evaluation segregation & production optimization of novel marine microalgae for establishment as live feeds in fish & shellfish culture (Co-PI)" (DBT- 2018 -2021 , Total outlay Rs.7091200)